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Record W2724207393 · doi:10.1093/chemse/bjx041

Nostril Differences in the Olfactory Performance in Health and Disease

2017· article· en· W2724207393 on OpenAlexaff
Daphnée Poupon, Thomas Hummel, Antje Haehner, Antje Welge‐Lüessen, Johannes Frasnelli

Bibliographic record

VenueChemical Senses · 2017
Typearticle
Languageen
FieldNeuroscience
TopicOlfactory and Sensory Function Studies
Canadian institutionsHôpital du Sacré-Cœur de MontréalUniversité du Québec à Trois-Rivières
Fundersnot available
KeywordsNostrilOlfactory systemAnosmiaContext (archaeology)OlfactionAudiologySensory systemNormativePsychologyNeuroscienceDiseaseMedicineNoseBiologyPathologyAnatomy

Abstract

fetched live from OpenAlex

In the past few decades, several olfactory tests have been developed to assess olfactory performance and detect disorders. Contrary to other sensory systems, both nostrils are usually tested together; we hypothesized that monorhinal testing may reveal side differences in sensitivity which may be useful for the diagnosis of olfactory dysfunction. Using the "Sniffin' Sticks" test, we assessed olfactory function of 458 participants (278 healthy controls, 180 hyposmic patients), one nostril after the other, with 3 different tasks. For each participant and each task, we compared the scores obtained with both nostrils, and defined the best and worst nostrils. Thus we were able to establish normative data and to define cut-off values. Our results suggest that scores obtained with the worst nostril are the most efficient in detecting an olfactory disorder. This supports the importance of monorhinal testing, as it can allow an earlier and more accurate diagnosis than birhinal testing. This may be especially useful in the context of early detection of neurodegenerative diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.216

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.228
GPT teacher head0.292
Teacher spread0.064 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2017
Admission routes1
Has abstractyes

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