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Record W2724593900 · doi:10.1093/geroni/igx004.633

SPATIAL, TEMPORAL, AND VARIABILITY NORMS FROM THE GAITRITE SYSTEM PREDICT MILD COGNITIVE IMPAIRMENT

2017· article· en· W2724593900 on OpenAlexaff
Timothy V. Lukyn, Sandra R. Hundza, Correne A. DeCarlo, R. A. Dixon, S. MacDonald

Bibliographic record

VenueInnovation in Aging · 2017
Typearticle
Languageen
FieldHealth Professions
TopicBalance, Gait, and Falls Prevention
Canadian institutionsUniversity of AlbertaUniversity of Victoria
Fundersnot available
KeywordsGaitDementiaCognitionSTRIDECognitive declinePhysical medicine and rehabilitationPsychologyCognitive impairmentEffects of sleep deprivation on cognitive performanceRegression analysisMedicineAudiologyStatisticsInternal medicinePsychiatryMathematics

Abstract

fetched live from OpenAlex

Mounting evidence indicates associations among temporal, spatial, and variability metrics of gait and clinical outcomes including fall risk, mild cognitive impairment (MCI), and movement disorders. Data from the Victoria Longitudinal Study (VLS) for select cohorts and retest waves were employed as a cross-sectional reference sample of older adults with intact cognitive performance and no history of falls. Participants (n=213) were 70 to 85 years of age (M=77.00, SD=4.22), with 152 women and 61 men. Regression-norming techniques were employed in the PREVENT Study, a multifactorial investigation of dementia, to identify participants with MCI. PREVENT participants (Controls=23, MCI=11) were 72 to 83 years of age (M=77.45, SD=4.23) with 20 women and 14 men. Select gait metrics were gathered from both samples using a 16-foot GAITRite computerized walkway. Participants walked across the mat at a self-determined normal pace a total of 8 times comprising 2 conditions: a walk-only condition (4 passes at a normal pace) and walking under cognitive load (4 passes counting backwards). The combination of velocity (under both conditions), single support time (walk-only) and Stride Time SD (walk-only) yielded a 90.6% MCI-classification accuracy (81.8% sensitivity; 95.2% specificity). Each SD increase in velocity under cognitive load was associated with a 25-fold decreased risk of MCI classification, while each SD increase in single support time was associated with a 17.75-fold increased risk. Findings provide strong preliminary evidence that regression-derived norms of specific GAITRite indicators can facilitate identification of MCI risk within an independent sample.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.357
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2017
Admission routes1
Has abstractyes

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