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Record W2724638186 · doi:10.1182/blood-2017-01-762336

Gemtuzumab ozogamicin in infants with AML: results from the Children’s Oncology Group trials AAML03P1 and AAML0531

2017· review· en· W2724638186 on OpenAlexaff
Erin Guest, Richard Aplenc, Lillian Sung, Susana C. Raimondi, Betsy Hirsch, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Jim Wang, Samir B. Kahwash, Amy Heerema‐McKenney, Soheil Meshinchi, Alan S. Gamis

Bibliographic record

VenueBlood · 2017
Typereview
Languageen
FieldMedicine
TopicAcute Myeloid Leukemia Research
Canadian institutionsHospital for Sick Children
FundersNational Cancer Institute
KeywordsGemtuzumab ozogamicinMedicineOncologyInternal medicineMyeloid leukemiaLeukemiaPediatricsClinical trialCD33

Abstract

fetched live from OpenAlex

To the editor: Infants younger than 1 year of age with acute myeloid leukemia (AML) often exhibit high-risk clinical and cytogenetic features.[1][1][⇓][2][⇓][3]-[4][4] They are also at increased risk of pulmonary and infectious toxicities, early death (ED), and treatment-related mortality (TRM

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.989
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0050.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.130
GPT teacher head0.417
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2017
Admission routes1
Has abstractyes

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