THE FATTY ACID-BINDING PROTEIN (fabp) GENES OF SPOTTED GREEN PUFFERFISH (TETRAODON NIGROVIRIDIS) - COMPARATIVE STRUCTURAL GENOMICS AND TISSUE-SPECIFIC DISTRIBUTION OF THEIR TRANSCRIPTS
Bibliographic record
Abstract
The fatty acid-binding protein (fabp) genes belong to the multigene family of intracellular lipid-binding proteins (iLBP). To date, 12 different FABPs have been identified in various vertebrate genomes. Owing to the fish-specific whole genome duplication (FSGD) event, many fishes have duplicated copies of the fabp genes. Here, I identified and characterized the fabp genes of spotted green pufferfish (Tetraodon nigroviridis). Initially, a BLAST search was performed and ten fabp genes were identified, out of which, three were retained in the pufferfish genome as duplicated copies. The putative pufferfish Fabp proteins shared greatest sequence identity and similarity with their teleost and tetrapod orthologs. Conserved gene synteny was evident between the pufferfish fabp genes and human, zebrafish, three-spined stickleback and medaka FABP/fabp genes, providing evidence that the duplicated copies of pufferfish fabp genes most likely arose as a result of the FSGD. The differential tissue-specific distribution of pufferfish fabp transcripts suggests divergent spatial regulation of duplicated pairs of fabp genes.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".