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Phytochemical screening and evaluation of cytotoxic activity of Pandanus fascicularis L. (Fruits)

2017· article· en· W2743848701 on OpenAlex
K. M. Rahat Maruf Jitu, Dipti Debnath, Sharmeen Asad, Rajib Das

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueDiscovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology · 2017
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicGABA and Rice Research
Canadian institutionsnot available
Fundersnot available
KeywordsPhytochemicalBrine shrimpGlycosideTraditional medicineBioassayPhenolsChloroformEthyl acetateChemistryPositive controlCytotoxic T cellBiologyChromatographyIn vitroBiochemistryStereochemistryMedicine

Abstract

fetched live from OpenAlex

The present study was conducted to evaluate possible phytochemicals present, and cytoctoxic activity of extract of fruits of Pandanus fascicularis L. Phytochemical screening was carried out using the standard test methods of different chemical group. Evaluation of cytotoxic activity was done using the brine shrimp lethality bioassay. The aqueous, methanolic, ethanolic, ethyl acetate, pet ether and chloroform extracts show presence of maximum phytochemicals such as alkaloids, tannins, flavonoids, steroids, saponins, proteins, terpens, phenols, glycosides, carbohydrate in different fractions etc. During cytotoxicity test, the positive control groups showed nonlinear mortality rates at lower concentrations and linear rates at higher concentrations. The LC50 values of Chloroform extract was found 1.0636 µg/ml where the positive control vincristine sulphate showed LC50 at a concentration of 0.200µg/ml. Therefore, the plant extract possess potent cytotoxic effect.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.408
Threshold uncertainty score0.489

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.149
GPT teacher head0.433
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it