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Elevated Translocator Protein in Anterior Cingulate in Major Depression and a Role for Inflammation in Suicidal Thinking: A Positron Emission Tomography Study

2017· article· en· 343 citations· W2743887053 on OpenAlex· 10.1016/j.biopsych.2017.08.005

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.020
GPT teacher head0.284
Teacher spread
0.264 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Biological Psychiatry
Topic
Tryptophan and brain disorders
Field
Neuroscience
Canadian institutions
Funders
Engineering and Physical Sciences Research CouncilNational Institute for Health and Care ResearchEuropean CommissionMinistère des relations internationales et de la Francophonie
Keywords
Translocator proteinAnterior cingulate cortexInsulaPrefrontal cortexPositron emission tomographyInternal medicinePsychologyCingulate cortexNeuroinflammationMicrogliaPosterior cingulateInflammationMajor depressive disorderMedicineNeuroscienceCortex (anatomy)EndocrinologyCognitionCentral nervous system
Has abstract in OpenAlex
no