Control of an HIV epidemic among injection drug users: simulation modeling on complex networks
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
HIV remains a serious public health problem in many marginalized communities. We develop a network model of the HIV epidemic affecting injection drug users and female sex workers in the Downtown Eastside neighborhood of Vancouver, Canada, calibrated using data from public health surveillance and cohort studies. Many HIV positive individuals are unaware of their status and strategies for testing are an important part of HIV response programs. Upon diagnosis, HIV patients enter a continuum of care, involving both engagement and retention in treatment. We explored potential epidemic control strategies through simulation: reduced syringe sharing during injection drug use, reduced time to diagnosis, reduced time to initiation of treatment following diagnosis, and improved retention in treatment. We find that syringe sharing, HIV testing, and retention in treatment significantly impact HIV prevalence. Close connections between syringe sharing and sexual networks deserve attention as important avenues for rapid HIV transmission.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it