MétaCan
Menu
Back to cohort
Record W2751134119 · doi:10.3920/wmj2017.2190

Single aflatoxin B1 exposure induces changes in gut microbiota community in C57Bl/6 mice

2017· article· en· W2751134119 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueWorld Mycotoxin Journal · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGut microbiota and health
Canadian institutionsCegep de Saint HyacintheUniversity of Guelph
FundersCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorUniversity of Guelph
KeywordsLachnospiraceaeAflatoxinMycotoxinGastrointestinal tractGut floraBiology16S ribosomal RNAMicrobiologyFood scienceGeneGeneticsFirmicutesImmunologyBiochemistry

Abstract

fetched live from OpenAlex

The liver and the gastrointestinal tract are the earliest target for the harmful effects of aflatoxin B 1 (AFB 1 ). This study investigated the impact of a single oral administration of AFB 1 (663 µg of AFB 1 /kg of body weight) on the gut microbial community of C57Bl/6 mice. Sequencing of the V4 region of the 16S rRNA gene was performed with an Illumina MiSeq sequencer. AFB 1 caused significant increases in the Lachnospiraceae family and decreases in Mucispirillum genus. In conclusion, a single oral dose of AFB 1 changed the relative abundances of some taxa, but not the overall membership or structure of intestinal microbial communities in C57Bl/6 mice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.396
Threshold uncertainty score0.983

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.290
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it