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Record W2757138218

HUMAN GENOME PROJECT

2005· article· en· W2757138218 on OpenAlexaboutno aff
Hetal B. Gavit

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsnot available
Fundersnot available
KeywordsHuman genomeInternational HapMap ProjectGenome projectGenomeReference genomeGovernment (linguistics)BiologyDNA sequencing1000 Genomes ProjectLibrary scienceGeneticsComputational biologyGeneComputer scienceSingle-nucleotide polymorphism
DOInot available

Abstract

fetched live from OpenAlex

The Human Genome Project (HGP) was an international scientific research project with a primary goal to determine sequence of chemical base pairs which make up DNA and to identify and map approximately 20,000–25,000 genes of human from both a physical and functional standpoint. The first available assembly of was completed in 2000 by UCSC Genome Bioinformatics Group, composed of Jim Kent (then a UCSC graduate student of molecular, cell and developmental biology), Patrick Gavin, Terrence Furey and David Kulp. The project began in 1990, initially headed by James D. Watson at U.S. National Institutes of Health. A working draft of was released in 2000 and a complete one in 2003, with further analysis still being published. A parallel project was conducted outside of government by Celera Corporation. Most of government-sponsored sequencing was performed in universities and research centers from United States, United Kingdom, Canada, and New Zealand. The mapping of human genes is an important step in development of medicines and other aspects of health care. The HGP originally aimed to map nucleotides contained in a haploid reference human (more than three billion). Several groups have announced efforts to extend this to diploid human genomes including International HapMap Project, Applied Biosystems, Perlegen, Illumina, JCVI, Personal Genome Project, and Roche-454. The of any given individual (except for identical twins and cloned organisms) is unique; mapping the human genome involves sequencing multiple variations of each gene. The project did not study entire DNA found in human cells; some heterochromatic areas (about 8% of total genome) remain un-sequenced.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.873
Threshold uncertainty score0.332

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.318
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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