Evaluation of Cerebral Oxygenation During Electrophysiological Studies
Bibliographic record
Abstract
To assess cerebral cortical oxygenation and cellular homeostasis during EPS and RF ablation, using near infrared spectroscopy. Standard EPS was performed in 11 sedated patients (female = 6, mean age = 45 ± 11 years) with symptomatic SVT documented on ECG and no pre-existing cardiovascular or cerebrovascular disease. A NIRO-300 spectrophotometer was used to continuously measure absolute changes in the concentrations of chromophores which reflect intravascular and mitochondrial levels of oxygenation, namely oxygenated haemoglobin (hbo2), deoxygenated haemoglobin (Hb) and the net redox status of cytochrome c oxidase (cyt-a,a3). MABP was monitored simultaneously. RF ablations were performed on 10 patients [AV nodal reentrant tachycardia=6; AV reentrant tachycardia= 4; cycle length = 348 ± 69 msec (range: 225-425 msec)]. No significant changes occurred in hbo2, Hb and cyt-a,a3 during atrial and ventricular EPS pacing protocols, induced SVT, or RF ablation. MABP decreased during pacing at cycle lengths < 400 msec (p<0.005). Cellular energy dynamics were stable during atrial and ventricular pacing, SVT, and RF ablation. This data suggests that overall cerebral tissue oxygenation is preserved during EPS.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".