144: New Baby Jitters: Novel Characterization of the Incidence and Risk Factors for Neonatal Hypoglycemia in the Premature Infant <33 Weeks.
Bibliographic record
Abstract
Neonatal hypoglycemia is common and prematurity is a well-recognized risk factor. However, the incidence of hypoglycemia in the premature infant <33 weeks gestation immediately after birth is unknown. To determine the incidence of hypoglycemia and associated risk factors in premature infants <33 weeks gestation. Patient information including maternal and infant risk factors was collected prospectively (June 2013 to September 2014) for the Sustained Inflation Randomized Controlled Trial. Neonates born with gestational age <33 weeks were included. Neonates were excluded if they had congenital anomalies or conditions that may adversely affect breathing or ventilation. Hypoglycemia was defined as blood glucose of ≤2.6 mmol/L on cord blood gas sampling collected in the delivery room within the first hour of delivery. There were 175 premature infants with mean (SD) gestational age of 28.1 (2.5) weeks, birth weight of 1169 (406) g, and 51% were male. A total of 6.6% of infants had intrauterine growth restriction (IUGR) defined as a birth weight <10th percentile. Overall 69 (39%) of the patients had hypoglycemia within the first hour of birth. Initial correlation studies suggested a relationship between glucose values and birth weight Z-score. Risk factors for hypoglycemia included IUGR and hypertension in pregnancy (Table 1). Labor before delivery was protective of hypoglycemia and antenatal administration of magnesium sulphate trended towards being protective but did not reach statistical significance. The administration of steroids prior to delivery, the administration of inotropes in the first 72 hours, and gender were not related to hypoglycemia. Neonatal hypoglycemia was not a risk factor for mortality in the Neonatal Intensive Care Unit (Relative Risk 0.91 P=1.00). This is the first report of incidence of hypoglycemia in premature infants <33 weeks. Hypoglycemia in premature infants <33 weeks gestation is common and risk factors include IUGR and hypertension in pregnancy. Protective factors against hypoglycemia included labour before birth and potentially the administration of antenatal magnesium sulphate.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".