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Record W2761973162 · doi:10.24870/cjb.2017-a168

Diagnosis and Curative Treatment for Liver Cirrhosis

2017· article· en· W2761973162 on OpenAlexvenueno aff
S. Sarath Raj, M. Ranjith

Bibliographic record

VenueCanadian Journal of Biotechnology · 2017
Typearticle
Languageen
FieldMedicine
TopicAlcohol Consumption and Health Effects
Canadian institutionsnot available
Fundersnot available
KeywordsCirrhosisMedicineGastroenterologyInternal medicine

Abstract

fetched live from OpenAlex

The main reason of Cirrhosis is the formation of thickened cell line with proteins called as FIBROTICS. Fibrosis means formation of excess of tissue as in a reparative or reactive process. Chronic scarring with liver results in damage to the reparative nodules which is severe and non-reversible. If it is allowed to continue, the buildup of scarred tissue can eventually stop the functions of the liver. Perisinusoidal space in the regenerative nodules has stellate cells which are present below the Hepatocytes and above the Sinusoid. Sinusoid carries the blood along with other cells. The stellate cells in the perisinusoidal space contain vitamin A (quiescent) which get activated after injury. These cells secrete TGF-β and produce collagen. In normal state liver carries wound healing process but when comes to constant injury, the collagen with fibrosis makes the stellate cells to enlarge resulting in the compression of the sinusoid. It creates a pressure in the sinusoid which moves the fluid from the sinusoid to peritoneal cavity that causes ASCITES, the one of the symptoms of cirrhosis. Further enlargement will cause congestive splenomegaly. This is the main reason for the diversion of blood to portosystemic shunt. This finally results in hepatorenal failure (liver failure). Our idea is to bring permanent cure and prevention to the liver cirrhosis by using Nano-robots. A Nano-robot is designed by ELECTRIC-BIOSENSOR. Mostly the nanoparticles present in the samples are used. Drugs like aspirin, dicumarol, and arsenicals destroy the vitamin A. The Nanobots carrying these samples detect the vitamin A and subsequently inactivates them. This leads to shrinking of the cells in the liver and cures the liver cirrhosis. It prevents the liver cirrhosis in starting stage itself.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.846
Threshold uncertainty score0.951

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.156
GPT teacher head0.390
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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