Role of Sex Hormones in the Control of Vegetative and Metabolic Functions of Middle-Aged Women
Bibliographic record
Abstract
Aims: In women’s life, menopause is characterized by significant physiological changes often associated with an increase in body weight and obesity-related diseases. Many studies have been carried out to determine interdependencies of estrogen depletion, aging, and resting energy expenditure (REE) decline in menopause-related obesity. Methodology: In this study, we measured the body composition, the REE, the oxidative stress, the food intake, and the activity of the autonomic nervous system of three groups: pre-menopause women (n=50), post-menopause women following hormone-replacement therapy (HRT; n=50), and post-menopause women not following HRT (n=50). Results: In post-menopause women with HRT a significant increase was found in: 1) the sympathetic activity, measured by the power spectral analysis of the heart rate variability; 2) REE, measured by indirect calorimetry; 3) oxidative stress, measured by FRAS 4 compared to the value of the other two, while fat mass, measured by BIA, was reduced in favor of a recovery of free fat mass. Conclusion: The study highlights the importance of the HRT-related physiological changes that influence body weight in menopause women.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".