Role of Sex Hormones in the Control of Vegetative and Metabolic Functions of Middle-Aged Women
Bibliographic record
Abstract
Aims: In women’s life, menopause is characterized by significant physiological changes often associated with an increase in body weight and obesity-related diseases. Many studies have been carried out to determine interdependencies of estrogen depletion, aging, and resting energy expenditure (REE) decline in menopause-related obesity. Methodology: In this study, we measured the body composition, the REE, the oxidative stress, the food intake, and the activity of the autonomic nervous system of three groups: pre-menopause women (n=50), post-menopause women following hormone-replacement therapy (HRT; n=50), and post-menopause women not following HRT (n=50). Results: In post-menopause women with HRT a significant increase was found in: 1) the sympathetic activity, measured by the power spectral analysis of the heart rate variability; 2) REE, measured by indirect calorimetry; 3) oxidative stress, measured by FRAS 4 compared to the value of the other two, while fat mass, measured by BIA, was reduced in favor of a recovery of free fat mass. Conclusion: The study highlights the importance of the HRT-related physiological changes that influence body weight in menopause women.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".