A 26-year-old man with ocular complications after adverse reaction to phenytoin
Bibliographic record
Abstract
A 26-year-old black man was admitted to the Burn Unit of Hamilton General Hospital, Ontario, following an adverse drug reaction to phenytoin. He was diagnosed with toxic epidermal necrolysis (TEN) and Ophthalmology was consulted to assess for ocular complications (Figure 1). The Score of Toxic Epidermal Necrosis (SCORTEN) for this patient was 2 (SCORTEN is a validated severity-of-illness score that is predictive of mortality; scores range from 0 to 7, with 2 corresponding to a 12.1% mortality rate), because he was <40 years of age, had no associated malignancy, had a heart rate of >120 beats/minute, no electrolyte abnormalities (blood urea nitrogen, serum glucose, or serum bicarbonate), and a detached body surface of >10%.(1) He had no comorbidities. His medical history was remarkable for epilepsy. The patient had 85% of his body covered in a thin vesicular slightly blistering rash. His systemic involvement included oral and orbital edema and ulceration of his lips, oral mucosa, scrotum, glans, and upper right chest.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".