A fast immune priming that confers a complete infection resistance on silkworm ( <i>Bombyx mori</i> )
Bibliographic record
Abstract
Abstract I have previously reported an immune priming in silkworm triggered by peptidoglycans, which is long-lasting but slow-acting. Here I report a faster immune priming, which can be triggered by an injection of gelatin or collagen, that confers a complete infection resistance to Gram-negative bacteria on silkworms. Gelatin-injected silkworms showed 100% viability in a lethal dose of a Gram-negative bacterial infection within two hours after the gelatin injection. Injection of collagen showed a similar effect. Whereas, an injection of non-gelatin protein (bovine serum albumin) solution did not induce such reaction. These results suggest that the silkworm possesses a fast and gelatin-inducible pathway that confers infection resistance to Gram-negative bacteria, which may act as a front-line defense. This finding highlights the potency of gelatin as a tool for investigating the primed immune responses in insect species.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".