Resistance to Dicarboximide Fungicides in a Canadian Population of <i>Microdochium nivale</i>
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Isolates of Microdochium nivale suspected of resistance to iprodione [3‐(3,5‐Dichlorophenyl)‐ N ‐isopropyl‐2,4‐dioxoimidazolidine‐1‐carboxamide] were collected from a golf course in Victoria, British Columbia (BC), Canada, in Fall 2015. The 9 BC isolates and 12 other reference isolates from around the world were tested with four concentrations of iprodione: 0, 1, 10, and 100 μg mL −1 . The BC isolates showed a half maximal effective concentration (EC 50 ) range of 14.2 to 40.8 μg mL −1 with a mean of 24.2 μg mL −1 , while the non‐BC isolates showed an EC 50 range of 1.2 to 4.3 μg mL −1 with a mean of 1.9 μg mL −1 . The yielded resistance factor (EC 50 resistant/EC 50 sensitive) of 12.7 implies that these BC isolates have been selected for reduced sensitivity to iprodione. This level of resistance may be responsible for the reduced efficacy, particularly the observed reduced interval of control, but further research is needed to assess this. A test of >100 isolates of M. nivale from a worldwide collection using a discriminatory concentration of 10 μg mL −1 of iprodione showed four isolates with similar levels of reduced sensitivity, but these were the only isolates from their respective populations.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it