Bibliographic record
Abstract
We suppose that at study of the pathogenesis of atherosclerosis, it is possible that some evolutionary aspects of the problem are missed. This aspect is related to the peculiarity of human adaptation to climatic geographic conditions of Eurasia, which differ significantly from the climate of East Africa, where Homo sapiens was formed as a tropical biological species and so it has remained to this day. A hypothesis has been put forward that the pathogenesis of atherosclerosis is associated with some previously unknown features of the genome and the physical properties of the human body that arose in the process of its adaptation to a mild and cold climate. These adaptive genetic changes that have contributed to the development (settling) by Homo sapiens of non-tropical, including cold and high mountain areas of the Earth, resulted to the fact that a man became the single species vulnerable (predisposed) to atherosclerosis.Atherosclerosis is apparently a purely human disease that appeared after adaptation of man to climatic conditions of temperate and northern latitudes of the northern hemisphere. The type of vessels (arteries or veins) and the site of their lumen have no role in the development of atherosclerotic changes. The primary and main causative factor in the development of atherosclerosis is blood temperature. The degree of blood cooling in the lungs depends on geographical latitudes and altitude above sea-level of the site of permanent residence of man. The preclinical stage of atherosclerosis may develop into a pathological form predominantly in individuals in the genome of which the amount of chromosomal Q-heterochromatin material is higher than its mean value per individual in the population.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".