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Record W2766376869 · doi:10.1002/jppr.1324

A case of quetiapine‐induced catatonia

2017· article· en· W2766376869 on OpenAlexaff
Grace L. Lucas, Adeleke D. Adewumi

Bibliographic record

VenueJournal of Pharmacy Practice and Research · 2017
Typearticle
Languageen
FieldMedicine
TopicElectroconvulsive Therapy Studies
Canadian institutionsSt Mary's Hospital Centre
Fundersnot available
KeywordsQuetiapineCatatoniaDiscontinuationMedicinePharmacovigilancePsychiatryQuetiapine FumarateBipolar disorderPediatricsSchizophrenia (object-oriented programming)Atypical antipsychoticDrugLithium (medication)

Abstract

fetched live from OpenAlex

Abstract Aim To present a case of catatonia on exposure to quetiapine. Clinical details We report the case of a 68‐year‐old man with bipolar affective disorder who experienced catatonia upon initiation of quetiapine on day 4 of his admission to hospital. He was commenced on quetiapine 50 mg at night which was increased to 100 mg the following night. He did not have a prior history of any reaction to the medication. Outcome symptoms Resolved upon discontinuation of quetiapine. Conclusion The importance of pharmacovigilance cannot be overemphasised. Clinicians need to be aware that catatonia may occur with the use of quetiapine and patients need to be closely monitored for unexpected reactions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0010.002
Open science0.0010.002
Research integrity0.0050.004
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.248
GPT teacher head0.576
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2017
Admission routes1
Has abstractyes

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