Abstract WP199: Outcome of Pregnancies and Deliveries Before and After Ischemic Stroke- A Retrospective Matched Cohort Study
Bibliographic record
Abstract
Introduction: Limited data exist on the outcome of pregnancies and deliveries among young women with ischemic stroke. Hypothesis: The incidence of pregnancy- and delivery-related complications in women who will suffer or have suffered an ischemic stroke differs from stroke-free controls. Methods: We included young female patients admitted for an ischemic stroke to the Department of Neurology, Helsinki University Central Hospital 1994-2007, with pregnancy data before or after stroke recorded in the Medical birth Register (MBR) (n=154), and their stroke-free controls matched with age, parity, year of birth, residential area, and multiple pregnancies (n=616). We obtained data 1987-2014 on pregnancies from the MBR, all-cause hospitalizations from the Hospital Discharge Register, and causes of deaths from Statistics Finland. We used Poisson regression mixed models to compare the incidence of pregnancy- and delivery-related complications over time both before and after stroke. Results: Among a total of 1400 singleton pregnancies and deliveries, the incidence rate ratio (IRR) for the composite outcome, including pre-eclampsia, eclampsia, small for gestational age, low birth weight, preterm birth, placental abruption, gestational diabetes, hospital care during pregnancy, death of the mother during pregnancy or puerperium, stillbirth, early neonatal death, Apgar at 1 minute 6 or less, and if the child was not at home at 7 days from the delivery, was 1.29 (95% confidence interval (CI) 1.00-1.65) for the mother with an impending stroke, or a history of stroke, or both, compared with the matched control mother. Similar results were obtained if the data were restricted to those women who became pregnant before or after stroke (IRR 1.25 and IRR 1.34, respectively). When adjusted for smoking and socioeconomic status, the IRR for the composite outcome was 1.31 (95% CI 0.99-1.73). Conclusions: There was a slight increase in the incidence of pregnancy- and delivery-related complications over time for mothers with an impending stroke, or a history of stroke, or both, compared with stroke-free mothers.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".