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Record W2766483708 · doi:10.2217/epi-2017-0106

The Epigenetic Landscape of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Deciphering Complex Phenotypes

2017· editorial· en· W2766483708 on OpenAlexaff
Wilfred C. de Vega, Patrick O. McGowan

Bibliographic record

VenueEpigenomics · 2017
Typeeditorial
Languageen
FieldMedicine
TopicFibromyalgia and Chronic Fatigue Syndrome Research
Canadian institutionsThe Scarborough HospitalUniversity of Toronto
Fundersnot available
KeywordsEpigeneticsPhenotypeBiologyHeritabilityDiseaseNeuroscienceEvolutionary biologyGeneticsMedicinePathology

Abstract

fetched live from OpenAlex

Our preliminary examinations of DNA methylation in ME/CFS have provided additional evidencefor a major immune component and distinct profiles among groups of patients."

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.011
Threshold uncertainty score0.035

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.015
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0020.001
Science and technology studies0.0020.002
Scholarly communication0.0040.005
Open science0.0030.002
Research integrity0.0110.023
Insufficient payload (model declined to judge)0.0040.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.318
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2017
Admission routes1
Has abstractyes

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