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Record W2766715687 · doi:10.1101/213173

Effects of the veterinary anthelmintic moxidectin on dung beetle survival and ecosystem functioning

2017· preprint· en· W2766715687 on OpenAlexaff
Paul Manning, Owen T. Lewis, Sarah A. Beynon

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2017
Typepreprint
Languageen
FieldVeterinary
TopicHelminth infection and control
Canadian institutionsDalhousie University
Fundersnot available
KeywordsMoxidectinBiologyDung beetleAnthelminticLivestockEcosystemInvertebrateZoologyAnimal scienceToxicologyEcologyScarabaeidae

Abstract

fetched live from OpenAlex

Abstract Macrocyclic lactones (MLs) are a class of chemical compounds administered to livestock for parasite control. These compounds are poorly metabolized and are predominately excreted in dung. When coprophagous insects such as dung beetles (Coleoptera: Scarabaeoidea) are exposed to ML residues, lethal and sublethal effects are often observed. Indirectly this can lead to ML residues impairing ecosystem functions that underpin production. A strategy to reduce these negative effects involves selecting compounds that offer lower risk to non-target invertebrates such as the ML moxidectin. Considering two dung beetle species with differing sensitivities to agricultural intensification, we asked whether exposure to moxidectin residues influenced survival, reproductive output, and functioning (short- and long-term estimates of dung removal). When exposed to moxidectin, adults of the sensitive species ( Geotrupes spiniger Marsham) experienced a 43% reduction in survival. In contrast, survival of the non-sensitive species ( Aphodius rufipes L.) was unaffected. We were unable to determine whether exposure affected reproductive output of either species. We found little evidence to suggest moxidectin impaired dung removal. We found however, that high densities of a species with relatively low functional importance ( A. rufipes ) can compensate for the loss of a functionally dominant species ( G. spiniger ). Over a longer timeframe, earthworms fully decomposed dung irrespective of moxidectin residues.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.795
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.256
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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