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Record W2766746643

Abstract 20654: An Estrogen Receptor α (ERα)-BMPR2-Apelin Axis Mediates 17β-Estradiol’s Protective Effects on Right Ventricular Function in Experimental Pulmonary Hypertension (PH)

2016· article· en· W2766746643 on OpenAlexaff
Andrea L. Frump, Margie Albrecht, Sandra Brueils-Bonnet, Jordan Whitson, Bakhtiyor Yakubov, Mary Beth Brown, Steeve Provencher, Sébastien Bonnet, Tim Lahm

Bibliographic record

VenueCirculation · 2016
Typearticle
Languageen
FieldMedicine
TopicApelin-related biomedical research
Canadian institutionsUniversité LavalInstitut universitaire de cardiologie et de pneumologie de Québec
Fundersnot available
KeywordsMedicineApelinPulmonary hypertensionInternal medicineEstrogenEstrogen receptorBMPR2EndocrinologyCardiologyVentricular functionReceptorBone morphogenetic proteinBiochemistry
DOInot available

Abstract

fetched live from OpenAlex

Introduction: Women with pulmonary arterial hypertension (PAH) exhibit superior RV function and survival compared to men, a phenomenon attributed to poorly understood cardioprotective effects of 17...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.792
Threshold uncertainty score0.819

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.275
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2016
Admission routes1
Has abstractyes

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