A Rare Presentation of Eosinophilic Granulomatosis with Polyangiitis with Diffuse Lymphadenopathy
Bibliographic record
Abstract
A 56-year-old man, who recently returned from a trip to Guyana, presented to hospital with a 10-week history of neuropathic pain, paresthesias, sinus pain, weight loss, and diffuse lymphadenopathy. Bloodwork was remarkable for significant eosinophilia (6.57 ×109 cells/L), erythrocyte sedimentation rate of 119 mm/hour and C-reactive protein of 44.3 mg/L. An extensive work up for an underlying lymphoproliferative disorder or infectious process was negative. Anti-MPO ANCA was initially borderline positive at 23 CU but on repeat testing 3 months later was strongly positive at 409 CU. He was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA) and was started on corticosteroids with an excellent clinical response. We review the epidemiology, typical clinical manifestations, diagnostic criteria and management of EGPA.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".