A Rare Presentation of Eosinophilic Granulomatosis with Polyangiitis with Diffuse Lymphadenopathy
Bibliographic record
Abstract
A 56-year-old man, who recently returned from a trip to Guyana, presented to hospital with a 10-week history of neuropathic pain, paresthesias, sinus pain, weight loss, and diffuse lymphadenopathy. Bloodwork was remarkable for significant eosinophilia (6.57 ×10 9 cells/L), erythrocyte sedimentation rate of 119 mm/hour and C-reactive protein of 44.3 mg/L. An extensive work up for an underlying lymphoproliferative disorder or infectious process was negative. Anti-MPO ANCA was initially borderline positive at 23 CU but on repeat testing 3 months later was strongly positive at 409 CU. He was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA) and was started on corticosteroids with an excellent clinical response. We review the epidemiology, typical clinical manifestations, diagnostic criteria and management of EGPA.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".