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Neurovegetative and cognitive impairments associated with anxiety in middle-aged patients with underlying cerebrovascular diseases

2017· article· en· W2768315425 on OpenAlex
T.I. Nasonova, О. В. Кліменко, Т. В. Колосова, Г. В. Горєва, Ю И Головченко, О. В. Тишкевич, О. М. Гурмак

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueFamily Medicine · 2017
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disorders and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsAnxietyMedicineCognitionInternal medicineTranquilizerNeuropsychologyEffects of sleep deprivation on cognitive performanceMontreal Cognitive AssessmentPsychiatryCognitive impairment

Abstract

fetched live from OpenAlex

The objective: analysis of the treatment efficacy and safety of neurovegetative and cognitive impairments associated with anxiety in middle-aged patients with underlying cerebrovascular diseases (CVD)by means of Adaptol® medication.Patients and methods. There were examined 60 patients, aged 42 to 58, having neurovegetative as well as light and mild cognitive impairments with underlying anxiety and depressive disorders (30 patients – main group, treatment with Adaptol® administration, 30 patients – control group: standard treatment without Adaptol® administration). The study of cognitive, vegetative and neuropsychological disorders was performed with the use of clinical scales. We determined the cortisol levels: before the treatment,on the 7th day of treatment and afterthis treatment.Results. It was determined that the patients with chronic cerebrovascular diseases CVD of young and middle-age, have mild to moderate cognitive impairments with underlying vegetative and anxiety disorders. Revealed impairments are corrected well by administering promptly of antihypertensive, metabolic, lipid lowering, and glucose–lowering therapy and also by means of minor tranquilizer Adaptol® produced by Olaynfarm company, at the dose of 300 mg twice a day for 28 days period. The treatment resulted in a statistically significant decrease of autonomic dysfunction, situational and personal anxiety and in the improved cognitive functions according to MoCa scale in patients taking Adaptol® in comparison to the data before the treatment. The level of cortisol in the blood plasma decreased gradually after 7 days of treatment and on the 28th day reached a statistically significant difference (p<0,05) when we compared the patients’ baseline parameters in the main group who received Adaptol® to those ones of the control group patients.Conclusions. Patients with early signs of chronic CVD were diagnosed with cognitive and anxiety disorders with underlying neuroveg etative syndrome which required treatment. Minor tranquilizer Adaptol® produced by Olaynfarm company is recommended for treatment of psycho emotional disorders in middle aged patients with underlying neurovegetative syndrome as a part of an anxiety disorder.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.598

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.284
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it