The effect of lipid levels on patient-reported outcomes in patients with rotator cuff tears
Bibliographic record
Abstract
BackgroundLipid disorders could be associated with the prevalence and outcomes of rotator cuff diseases. This study aimed to learn how levels of various types of lipids influence the patient-reported outcomes of patients with rotator cuff tears (RCTs).MethodsData from a cohort study of 135 patients with RCTs were used. The outcome measures included Western Ontario Rotator Cuff (WORC) index, American Shoulder and Elbow Surgeons (ASES) standardized shoulder assessment form, Single Assessment Numeric Evaluation, visual analog scale for pain and satisfaction, and Veterans RAND 12-Item Health Survey (VR-12). Multivariable random-effects models were built to examine how total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein, and ratio of total cholesterol to HDL influence each outcome, controlling for covariates.ResultsAfter adjusting for age, gender, surgery, smoking, and baseline outcome values, patients with triglycerides >150 mg/dL had significantly higher pain visual analog scale (β = 5.86; P = .017) and lower VR-12 physical component summary (β = −2.71; P = .002) scores. Patients with low HDL had significantly worse WORC (β = 132.26; P = .020) and ASES (β = −7.05; P = .005) scores, more pain (β = 6.69; P = .024), and less satisfaction (β = −6.53; P = .008). The ratio of total cholesterol to HDL was associated with worse WORC (β = 58.46; P = .006) and ASES scores (β = −2.74; P = .002), more pain (β = 4.49; P < .001), and worse VR-12 physical component summary score (β = −1.03; P = .017).ConclusionsDyslipidemia may decrease the improvement of patient-reported outcomes in patients undergoing treatment for RCTs; high triglycerides and low HDL may have the most impact. Lipid disorders could be associated with the prevalence and outcomes of rotator cuff diseases. This study aimed to learn how levels of various types of lipids influence the patient-reported outcomes of patients with rotator cuff tears (RCTs). Data from a cohort study of 135 patients with RCTs were used. The outcome measures included Western Ontario Rotator Cuff (WORC) index, American Shoulder and Elbow Surgeons (ASES) standardized shoulder assessment form, Single Assessment Numeric Evaluation, visual analog scale for pain and satisfaction, and Veterans RAND 12-Item Health Survey (VR-12). Multivariable random-effects models were built to examine how total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein, and ratio of total cholesterol to HDL influence each outcome, controlling for covariates. After adjusting for age, gender, surgery, smoking, and baseline outcome values, patients with triglycerides >150 mg/dL had significantly higher pain visual analog scale (β = 5.86; P = .017) and lower VR-12 physical component summary (β = −2.71; P = .002) scores. Patients with low HDL had significantly worse WORC (β = 132.26; P = .020) and ASES (β = −7.05; P = .005) scores, more pain (β = 6.69; P = .024), and less satisfaction (β = −6.53; P = .008). The ratio of total cholesterol to HDL was associated with worse WORC (β = 58.46; P = .006) and ASES scores (β = −2.74; P = .002), more pain (β = 4.49; P < .001), and worse VR-12 physical component summary score (β = −1.03; P = .017). Dyslipidemia may decrease the improvement of patient-reported outcomes in patients undergoing treatment for RCTs; high triglycerides and low HDL may have the most impact.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".