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Record W2770240606 · doi:10.1111/apa.14154

Systematic review of the effect of denosumab on children with osteogenesis imperfecta showed inconsistent findings

2017· review· en· W2770240606 on OpenAlexaff
Guowei Li, Yanling Jin, Mitchell Levine, Heike Hoyer‐Kuhn, Leanne M. Ward, Jonathan D. Adachi

Bibliographic record

VenueActa Paediatrica · 2017
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicConnective tissue disorders research
Canadian institutionsSt. Joseph’s Healthcare HamiltonMcMaster UniversityChildren's Hospital of Eastern OntarioImpactPrograms for Assessment of Technology in Health Research Institute
Fundersnot available
KeywordsMedicineOsteogenesis imperfectaFamily medicineAnatomy

Abstract

fetched live from OpenAlex

Heike Hoyer-Kuhn worked as a consultant without honoraria for Amgen. Jonathan D Adachi has been a consultant, speaker and performed clinical trial for Amgen, Eli Lilly, GlaxoSmithKline, Merck, Novartis, Pfizer, Procter and Gamble, Roche, Sanofi-aventis, Wyeth and Bristol-Myers Squibb. He has also been a consultant and speaker for Astra Zeneca, Nycomed and Servier. The other authors have no conflicts of interest to declare.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.029
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.029
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0060.006
Bibliometrics0.0040.006
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.319
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2017
Admission routes1
Has abstractyes

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