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Record W2772102885 · doi:10.1016/j.bpsc.2017.11.012

Subjective Cognitive Decline Is Associated With Altered Default Mode Network Connectivity in Individuals With a Family History of Alzheimer’s Disease

2017· article· en· W2772102885 on OpenAlexafffund
Sander C.J. Verfaillie, Alexa Pichet Binette, Étienne Vachon‐Presseau, Shirin Tabrizi, Mélissa Savard, Pierre Bellec, Rik Ossenkoppele, Philip Scheltens, Wiesje M. van der Flier, John C.S. Breitner, Sylvia Villeneuve, Paul Aisen, Elena Anthal, Melissa Appleby, Gülebru Ayrancı, Alan Barkun, Thomas Beaudry, Fatiha Benbouhoud, Véronique D. Bohbot, Jason Brandt, Leopoldina Carmo, Edouard Carrier Charles, M. Mallar Chakravarty, Laksanun Cheewakriengkrai, D. Louis Collins, Blandine Courcot, Doris Couture, Suzanne Craft, A. Claudio Cuello, Mahsa Dadar, Christian Dansereau, DasSamir, Marina Dauar‐Tedeschi, Doris Dea, Clément Debacker, René Desautels, Sylvie Dubuc, Guerda Duclair, Marianne Dufour, Mark Eisenberg, Rana El‐Khoury, Pierre Étienne, Alan C. Evans, Anne‐Marie Faubert, Fabiola Ferdinand, Vladimir Fonov, David Fontaine, Josée Frappier, Joanne Frenette, Guylaine Gagné, Serge Gauthier, Valérie Gervais, Renuka Giles, Julie Gonneaud, Renee Gordon, Rick Hoge, Bradley T. Hyman, Yasser Ituria‐Medina, Clifford R. Jack, Justin Kat, Christina Kazazian, Zaven S. Khachaturian, David S. Knopman, Penelope Kostopoulos, Anne Labonté, Marie‐Élyse Lafaille‐Magnan, Tanya Lee, Jeannie‐Marie Leoutsakos, Claude Lepage, Illana Leppert, Cécile Madjar, Laura Mahar, David Maillet, Jean‐Robert Maltais, Axel Mathieu, Sulantha Mathotaarachchi, Gerhard Maultaup, Ginette Mayrand, Pierre‐François Meyer, Diane Michaud, Justin Miron, Thomas J. Montine, John C. Morris, Lisa Marie Munter, Vasavan Nair, Jamie Near, Holly Newbold‐Fox, Pierre Orban, Véronique Pagé, Tharick A. Pascoal, Mirela Petkova, Cynthia Picard, Galina Pogossova, Judes Poirier, Jens C. Pruessner, Natasha Rajah, Pierre Rioux, Pedro Rosa‐Neto, Mark A. Sager, Eunice Farah Saint‐Fort, Reisa Sperling, Angela Tam, Christine Tardif, Pierre N. Tariot, Eduard Teigner, Louise Théroux, Ronald G. Thomas, Paule‐Joanne Toussaint, Jennifer Tremblay‐Mercier, Miranda Tuwaig, Isabelle Vallée, Vinod Venugopalan, Jacob W. Vogel, Karen Wan, Seqian Wang, Elsa Yu

Bibliographic record

VenueBiological Psychiatry Cognitive Neuroscience and Neuroimaging · 2017
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsInstitut Universitaire de Gériatrie de MontréalUniversité de MontréalMontreal Neurological Institute and HospitalDouglas Mental Health University InstituteMcGill University
FundersCanadian Institutes of Health Research
KeywordsDefault mode networkCognitive declineDiseaseFamily historyCognitionAlzheimer's diseasePsychologyGerontologyMedicineNeurosciencePsychiatryDementiaInternal medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.098
GPT teacher head0.320
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations74
Published2017
Admission routes2
Has abstractno

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