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Record W2774425008 · doi:10.3201/eid2401.170484

High Seroprevalence of Jamestown Canyon Virus among Deer and Humans, Nova Scotia, Canada

2017· article· en· W2774425008 on OpenAlexaboutno aff
Glenn Patriquin, Michael Drebot, Teri J. Cole, L. Robbin Lindsay, Emily Schleihauf, Bree Johnston, Kristina Dimitrova, Maya Traykova-Andonova, Angela Mask, David Haldane, Todd F. Hatchette

Bibliographic record

VenueEmerging infectious diseases · 2017
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Disease Management and Epidemiology
Canadian institutionsnot available
Fundersnot available
KeywordsNova scotiaSeroprevalenceCanyonGeographyVirologyNova (rocket)BiologyZoologyArchaeologySerologyCartographyImmunologyAntibody

Abstract

fetched live from OpenAlex

Using residual serum samples from Nova Scotia, Canada, we found that 87.8% of tested deer and an estimated 20.6% of the human population were infected with Jamestown Canyon virus.Human seropositivity reached 48.2% in 1 region.This virus may be an underrecognized cause of disease in Nova Scotia. J amestown Canyon virus (JCV), a mosquitoborne arbo-virus, belongs to the California serogroup (CSG) in the Bunyaviridae family.The primary reservoir host for JCV is considered to be the white-tailed deer, although JCV antibodies have been observed in other mammals, including horses, sheep, and cattle (1).JCV-associated illness among humans is rarely documented; rates of ≤0.01 cases/100,000 population have been reported in the United States (2,3).Infections can be asymptomatic or associated with a variety of manifestations, including fever, headache, myalgia, weakness, and seizure (4-6).Evidence of JCV in Atlantic Canada was reported in 1981 when 6 of 289 hunter-killed moose during the 1977-1978 hunting season in Nova Scotia (NS) were seropositive (7).There is no surveillance for JCV in NS, nor is it on the list of diseases notifiable to Provincial Public Health as defined in the NS Health Protection Act (8), but it could be reported as an unusual disease occurance or a disease occuring more frequently than expected.We undertook this study to determine the seroprevalence of JCV in humans and white-tailed deer in this province.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.026
Threshold uncertainty score0.052

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.232
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations24
Published2017
Admission routes1
Has abstractyes

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