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Applications of Support Vector Machine (SVM) Learning in Cancer Genomics

2018· review· en· 1,539 citations· W2778455075 on OpenAlex· 10.21873/cgp.20063

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Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

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Opus teacher head0.031
GPT teacher head0.339
Teacher spread
0.309 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Machine learning with maximization (support) of separating margin (vector), called support vector machine (SVM) learning, is a powerful classification tool that has been used for cancer genomic classification or subtyping. Today, as advancements in high-throughput technologies lead to production of large amounts of genomic and epigenomic data, the classification feature of SVMs is expanding its use in cancer genomics, leading to the discovery of new biomarkers, new drug targets, and a better understanding of cancer driver genes. Herein we reviewed the recent progress of SVMs in cancer genomic studies. We intend to comprehend the strength of the SVM learning and its future perspective in cancer genomic applications.

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The record

Venue
Cancer Genomics & Proteomics
Topic
Gene expression and cancer classification
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
University of ManitobaResearch Institute in Oncology and HematologyCancerCare Manitoba
Funders
CancerCare Manitoba Foundation
Keywords
Support vector machineArtificial intelligenceComputer scienceGenomicsMachine learningEpigenomicsFeature (linguistics)Margin (machine learning)Computational biologyGenomeBiologyGeneGene expressionGeneticsDNA methylation
Has abstract in OpenAlex
yes