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Validating production of PET radionuclides in solid and liquid targets: Comparing Geant4 predictions with FLUKA and measurements

2017· article· en· W2779069225 on OpenAlexafffund
T. Amin, Angelo Infantino, R. J. Barlow, Cornelia Hoehr

Bibliographic record

VenueApplied Radiation and Isotopes · 2017
Typearticle
Languageen
FieldMedicine
TopicRadiation Therapy and Dosimetry
Canadian institutionsTRIUMF
FundersTRIUMF
KeywordsMonte Carlo methodCyclotronRadionuclideProtonPhysicsProton therapyNuclear physicsIsotopeRadiochemistryMaterials scienceNuclear medicineChemistryMedicineMathematicsStatisticsElectron

Abstract

fetched live from OpenAlex

The Monte Carlo toolkit Geant4 is used to simulate the production of a number of positron emitting radionuclides: 13 N, 18 F, 44 Sc, 52 Mn, 55 Co 61 Cu, 68 Ga, 86 Y, 89 Zr and 94 Tc, which have been produced using a 13 MeV medical cyclotron. The results are compared to previous simulations with the Monte Carlo code FLUKA and experimental measurements. The comparison shows variable degrees of agreement for different isotopes. The mean absolute deviation of Monte Carlo results from experiments was 1.4 ± 1.6 for FLUKA and 0.7 ± 0.5 for Geant4 using TENDL cross sections with QGSP-BIC-AllHP physics. Both agree well within the large error, which is due to the uncertainties present in both experimentally determined and theoretical reaction cross sections. Overall, Geant4 has been confirmed as a tool to simulate radionuclide production at low proton energy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.284
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2017
Admission routes2
Has abstractyes

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