Variant Creutzfeldt-Jakob disease in a Canadian resident
Bibliographic record
Abstract
Variant Creutzfeldt-Jakob disease (vCJD) has been confirmed in a resident of Saskatchewan, Canada (1). The patient, a man under the age of 50, was first notified to the Canadian national CJD surveillance system at Health Canada in April 2002 when his clinical presentation, age, and history of residence in the United Kingdom (UK) led Canadian doctors to suspect vCJD. Post-mortem examination of brain tissues by experts in Canada and the UK has now confirmed the diagnosis of vCJD. Since 1998, when the national CJD surveillance system was launched, all suspect cases of CJD are reported to Health Canada through a national network of specialist physicians. Incidence data are also shared with European and other allied countries as part of the Collaborative Study Group of CJD (EUROCJD, http://www.eurocjd.ed.ac.uk/euroindex.htm). This patient is the first case of vCJD reported in Canada, which together with 6 cases reported in France and one each in the Republic of Ireland, Italy and USA, brings the total number of cases with onset outside the UK to 10 (personal communication National CJD Surveillance Unit, Edinburgh).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.013 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.002 | 0.003 |
| Insufficient payload (model declined to judge) | 0.005 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".