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Randomized controlled trial of an intervention to facilitate early mobilization after colorectal surgery: Impact on postoperative pulmonary function and complications

2017· article· en· W2780801574 on OpenAlexaff
Julio F. Fiore, Tanya Castelino, Nicolò Pecorelli, Petru Niculiseanu, Mohsen Alhashemi, Olivia Hershorn, Sender Liberman, Patrick Charlebois, Barry Stein, Franco Carli, Nancy E. Mayo, Liane S. Feldman, Saba Balvardi

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicEnhanced Recovery After Surgery
Canadian institutionsMcGill University
Fundersnot available
KeywordsMedicineRandomized controlled trialVital capacityPerioperativePulmonary function testingMobilizationColorectal surgeryLung functionSurgeryPhysical therapyLungInternal medicineAbdominal surgery

Abstract

fetched live from OpenAlex

<b>Background:</b> Early mobilization is believed to improve pulmonary function and prevent postoperative pulmonary complications (PPCs) but adherence is low. The value of allocating resources (e.g. staff time) to increase early mobilization is unknown. This study aimed to estimate the extent to which staff-directed facilitation of early mobilization impact on recovery of pulmonary function after colorectal surgery. We also explored the association of the intervention with 30-day PPCs. <b>Methods:</b> Pre-planned analysis of secondary outcomes of a randomized controlled trial (Fiore Jr et al. Ann Surg 2016 [ahead of print]). Patients undergoing colorectal surgery were randomized 1:1 to usual care (preoperative education) or facilitated mobilization (staff dedicated to assist transfers and walking during hospital stay). Forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and peak cough flow (PCF) were measured preoperatively and at 1, 2, 3 days and 4 weeks after surgery. PPCs were defined according to the European Perioperative Clinical Outcome Taskforce. <b>Results:</b> 99 patients were randomized (57% male, 80% laparoscopic, median age 63 and predicted FEV1 97%). There was no between-group difference in recovery of FVC [adjusted difference in slopes 0.002 L/day (95% CI -0.01 to 0.01)], FEV1 [-0.002 L/s/day (-0.01 to 0.06)] or PCF [-0.003 L/s/day (-0.02 to 0.02)]. 30-day PPCs were also not different between groups [adjusted odd ratio 0.56 (0.18 to 1.71)]. <b>Conclusion:</b> This study does not support the need to allocate resources for enhancing early mobilization to improve pulmonary outcomes after colorectal surgery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.363
Threshold uncertainty score0.487

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.307
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2017
Admission routes1
Has abstractyes

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