Atypical Sjögren presentation of pruriginous rash and mild eosinophilia with minor sicca symptoms: A case report
Bibliographic record
Abstract
We report a case of an 82-year-old woman diagnosed with Sjögren syndrome on the basis of salivary gland biopsy and anti-Ro/SSA antibodies who presented to our institution with a pruriginous maculopapular pancorporeal rash with diffuse eosinophilic infiltrate and mild eosinophilia. Sicca symptoms were mild. Cutaneous and hematologic findings resolved spontaneously within 4 weeks, the rash did not respond to antihistamines but was mildly attenuated by topical corticosteroid. Both the rash and hypereosinophilia greatly improved while the patient received oral corticosteroids for a contrast medium allergy before a CT-scan. When the patient was diagnosed with SS, hydroxychloroquine treatment was introduced. This case report aims to raise awareness of the possibility of such a clinical presentation, considering the known increased risk of non-hodgkin lymphoma associated with Sjögren syndrome estimated to 5%-10% lifetime risk which is 5 to 44 times higher than that of the general population.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".