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Phytochemical Investigation and Antimicrobial Evaluation of Foeniculum vulgare Leaves Extract Ingredient of Ethiopian Local Liquor

2018· article· en· W2787748642 on OpenAlexvenueno aff
Mohammed Seid, Aman Dekebo, Neelaiah Babu

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2018
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicEssential Oils and Antimicrobial Activity
Canadian institutionsnot available
Fundersnot available
KeywordsFoeniculumAntimicrobialPhytochemicalTraditional medicineBiologyFood scienceTerpenoidChemistryBotanyMicrobiology

Abstract

fetched live from OpenAlex

Medicinal plants are of great interest to the researcher in the field of biotechnology, as natural products, including medicinal plants, accounts 25% of prescribed drugs. Plants are sources for fragrances, drink colors and flavors in several countries including Ethiopia. All parts of Foeniculum vulgare were traditionally used as antispasmodic, aromatic, carminative, digestive, galactagogues, stomach and kidney ailment. Foeniculum vulgare leaves extract was investigated for its phytochemicals as well as antimicrobial effects. The petroleum ether, CHCl3, CHCl3/CH3OH (1:1) and CH3OH crude extract were subjected to phytochemicals screening test which revealed that it is rich in any primary and secondary metabolites such as steroids, tannins, flavonoids, cholesterol, terpenoids, saponins, phenols, cardiac glycosides, carbohydrates, and proteins. The essential oil of the plant leaves was investigated by GC?MS and was found to have (64.92%) anethole, as a major constituent followed by (30.88%) estragole and (3.21%) fenchyl acetate. The crude extracts, oil, and the isolated compound were tested against four bacterial species (Gram negative bacteria, Escherichia coli and Shigella flexneri; Gram positive bacteria: Staphylococcus aureus and Streptococcus pyrogenes) and two fungal species (Fusarium oxysporum and Aspergillus niger) using paper disc diffusion method. Tests of antimicrobial activity showed that all crude extracts and isolated pure compound were active against all the tested bacterial and fungal species. However, the hydrodistillation extract was found to have no antibacterial activity towards the tested bacterial species but active against the two fungal species and thus the present study supported the traditional claims of the plant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.342

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.327
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2018
Admission routes1
Has abstractyes

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