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Record W2788681334 · doi:10.1016/j.cell.2018.01.038

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases

2018· article· en· W2788681334 on OpenAlexafffund
Livia Garzia, Noriyuki Kijima, A. Sorana Morrissy, Pasqualino De Antonellis, Ana Guerreiro Stücklin, Borja Holgado, Xiaochong Wu, Xin Wang, Kory Zayne, Alex Manno, Claudia M. Kuzan-Fischer, Carolina Nör, Laura Donovan, Jessica Liu, Lei Qin, Alexandra Garancher, Kun-Wei Liu, Sheila Mansouri, Betty Luu, Yuan Thompson, Vijay Ramaswamy, John Peacock, Hamza Farooq, Patryk Skowron, David Shih, Angela Li, Sherine Ensan, Clinton S. Robbins, Myron I. Cybulsky, Siddhartha S. Mitra, Yussanne Ma, Richard A. Moore, Yoon-Jae Cho, William A. Weiss, Jennifer A. Chan, Cynthia Hawkins, Maura Massimino, Nada Jabado, Michal Zápotocký, David Sumerauer, Éric Bouffet, Peter B. Dirks, Uri Tabori, Poul H. Sorensen, Priscilla K. Brastianos, Kenneth Aldape, Steven J.M. Jones, Marco A. Marra, James R. Woodgett, Robert J. Wechsler‐Reya, Daniel W. Fults, Michael D. Taylor

Bibliographic record

VenueCell · 2018
Typearticle
Languageen
FieldMedicine
TopicBrain Metastases and Treatment
Canadian institutionsMcGill UniversityLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalPrincess Margaret Cancer CentreUniversity of CalgaryCanada's Michael Smith Genome Sciences CentreSickKids FoundationBC Cancer AgencyUniversity Health NetworkUniversity of TorontoUniversity of British ColumbiaHospital for Sick Children
FundersCanadian Institutes of Health ResearchGenome British ColumbiaStand Up To CancerNational Cancer InstituteUniversity of TorontoAlberta Innovates - Health SolutionsCanadian Cancer Society Research InstituteNational Institutes of HealthOntario Institute for Cancer ResearchGovernment of CanadaGovernment of OntarioTerry Fox Research InstituteHuntsman Cancer FoundationGenome Canada
KeywordsBiologyMedulloblastomaCancer research

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.294
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations144
Published2018
Admission routes2
Has abstractno

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