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Record W2789246307 · doi:10.1109/isscc.2018.8310297

50nW 5kHz-BW opamp-less ΔΣ impedance analyzer for brain neurochemistry monitoring

2018· article· en· W2789246307 on OpenAlexaff
Maged El Ansary, Nima Soltani, Hossein Kassiri, Ruben Machado, Suzie Dufou, Peter L. Carlen, Michael Thompson, Roman Genov

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldChemical Engineering
TopicAnalytical Chemistry and Sensors
Canadian institutionsToronto Western HospitalUniversity of Toronto
Fundersnot available
KeywordsIon channelNeuroscienceNeuronNervous systemEpilepsyChemistrySodiumSodium channelInternal medicineMedicinePsychologyReceptor

Abstract

fetched live from OpenAlex

Potassium (K+) and sodium (Na+) ions are the main signal carriers in the nervous system. The difference in the concentration of both K+ and Na+ across the neuron cell membrane, as regulated by respective ion channels, plays a critical role in the propagation of action potentials, the spike-like signals neurons communicate with, as shown in Fig. 17.5.1 (top, left and middle). Due to their significant role in neuronal signaling, K+ channel malfunctions are linked to over 100 neurological disorders, such as schizophrenia, Alzheimer's disease, spreading depression, and epilepsy. Selective real-time sensing of K+ concentration (denoted as [K+]) is therefore critical for the advancement of many neurological therapies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.077
Threshold uncertainty score0.257

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0770.018

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.285
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2018
Admission routes1
Has abstractyes

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