A120 PREVALENCE OF ANXIETY AND DEPRESSION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
Bibliographic record
Abstract
Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life. We aim to determine the prevalence of anxiety and depression in IBD patients. The prevalence of anxiety and depression was assessed in outpatients with IBD attending a clinic associated with a tertiary teaching hospital (St. Paul’s Hospital, Vancouver, Canada) through retrospective chart review. The presence of anxiety and/or depression was determined using the Patient Health Questionnaire – 9 and Generalized Anxiety Disorder – 7 self-report questionnaires (administered routinely to patients attending the clinic), with a score above 10 considered a positive result. Patients were also considered to have depression or anxiety if diagnosed by psychiatric interview after referral to a psychiatrist. Information regarding patient demographics, disease characteristics and medications was also collected. Disease activity was defined using the Partial Mayo Score (UC) or Harvey- Bradshaw Index (CD) where patients with a score within the moderate or severe range were considered to have active disease. Multivariable analysis was used to determine associations between patient factors and depression and anxiety. 327 patient charts were reviewed. The study population was 49.8% female, 37.9% had Ulcerative Colitis and 62.1% Crohn’s Disease, mean age was 38.72 +/- 14.44, and mean time since diagnosis 10.96 years +/- 8.64. The rates of depression and anxiety were found to be 25.8% and 21.2% respectively, with 30.3% of patients suffering from depression and/or anxiety. Three percent of patients were on steroids and 61% were previously or currently on biologics. Approximately 13% of patients had active disease at the time of assessment. Disease activity was found to be significantly associated with depression and/or anxiety (p=0.01). Females were more likely to have anxiety (p=0.01). A significant proportion of IBD patients suffer from depression and/or anxiety. The rates of these mental illnesses would justify screening and referral for psychiatric treatment in clinics treating this population. Patients with active disease are particularly at risk for mental health sequelae and should therefore be paid extra attention in screening and treatment efforts. None
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".