IMPACT OF INTRA-OPERATIVE SEDATION WITH SPINAL ANESTHESIA DURING UTERUS AMPUTATION ON COGNITIVE FUNCTIONS IN THE POST-OPERATIVE PERIOD
Bibliographic record
Abstract
The post-operative cognitive dysfunction is an adverse disorder of higher functions of the nervous system, which develops in the post-operative period and it is associated with surgery and anesthesia. The goal: to investigate the impact of sedation through spinal anesthesia on the frequency of the post-operative cognitive dysfunction after uterus amputation. Subjects and methods. 65 middle age women were examined, they all had the uterus amputated with spinal anesthesia with 15-20 mg of 0.5% hyperbaric solution of bupivicaine. Dexmedetomidine (0.5-1.2 mcg/kg per 1 hour) was used in the patients from Group 1 (28 women), and propofol (2-10 mg/kg per 1 hour) was used in Group 2 (37 women). Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were used for assessment of cognitive functions before and after the surgery. Results. The statistically significant difference in the level of cognitive functions was observed between the Groups on the 1st and 5th day after the surgery. The level of cognitive functions was statistically significantly higher in the group where dexmedetomidine was used versus the group where propofol was used, which provided the evidence of the minimum negative effect of spinal anesthesia with dexmedetomidine on the cognitive potential in the patients undergoing gynecological surgery. Conclusion: Spinal anesthesia with dexmedetomidine during uterus amputation reduces the risk of the post-operative cognitive dysfunction.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".