Otic Langerhans Cell Histiocytosis in Adults: A Report of Two Cases
Bibliographic record
Abstract
We presented two cases of Langerhans cell histiocytosis (LCH) in which the temporal bone and hearing center in the brain stem were affected. We discuss the diagnosis and management of this disease and how it presents if the temporal bone is involved. The first case involved a patient with destructive lesions in the temporal bone, who responded to medical management, while the second case involved a patient with brain stem lesions, who did not improve on chemotherapy. The findings from these two cases suggest that a differential diagnosis of LCH should be considered in patients with persistent ear discharge or hearing loss that does not respond to conventional antibiotic treatment, and that imaging studies are required for any atypical presentation. J Med Cases. 2018;9(3):106-108 doi: https://doi.org/10.14740/jmc2917w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".