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Record W2794154499 · doi:10.1111/jvh.12875

Hepatitis C: The beginning of the end—key elements for successful European and national strategies to eliminate HCV in Europe

2018· review· en· W2794154499 on OpenAlexaff
George Papatheodoridis, Angelos Hatzakis, Εvangelos Cholongitas, Ricardo Baptista‐Leite, I. Baskozos, Jagpreet Chhatwal, Massimo Colombo, Helena Cortez‐Pinto, Antonio Craxı̀, David Goldberg, Charles Gore, Achim Kautz, Jeffrey V. Lazarus, Luís Mendão, Markus Peck‐Radosavljevic, Homie Razavi, Eberhard Schatz, Nurdan Tözün, Pierre Van Damme, Heiner Wedemeyer, Yazdan Yazdanpanah, Freke Zuure, Michael P. Manns

Bibliographic record

VenueJournal of Viral Hepatitis · 2018
Typereview
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsInstitute of Infection and Immunity
FundersAbbVieGilead Sciences
KeywordsEuropean unionSummitManifestoPublic healthHepatitis CPolitical scienceMedicineVirologyEnvironmental healthEconomic growthPublic administrationBusinessGeographyInternational tradeEconomicsLaw

Abstract

fetched live from OpenAlex

Hepatitis C virus (HCV) infection is a major public health problem in the European Union (EU). An estimated 5.6 million Europeans are chronically infected with a wide range of variation in prevalence across European Union countries. Although HCV continues to spread as a largely "silent pandemic," its elimination is made possible through the availability of the new antiviral drugs and the implementation of prevention practices. On 17 February 2016, the Hepatitis B & C Public Policy Association held the first EU HCV Policy Summit in Brussels. This summit was an historic event as it was the first high-level conference focusing on the elimination of HCV at the European Union level. The meeting brought together the main stakeholders in the field of HCV: clinicians, patient advocacy groups, representatives of key institutions and regional bodies from across European Union; it served as a platform for one of the most significant disease elimination campaigns in Europe and culminated in the presentation of the HCV Elimination Manifesto, calling for the elimination of HCV in Europe by 2030. The launch of the Elimination Manifesto provides a starting point for action in order to make HCV and its elimination in Europe an explicit public health priority, to ensure that patients, civil society groups and other relevant stakeholders will be directly involved in developing and implementing HCV elimination strategies, to pay particular attention to the links between hepatitis C and social marginalization and to introduce a European Hepatitis Awareness Week.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.050
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.050
Threshold uncertainty score0.266

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0500.025
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0030.007
Scholarly communication0.0150.013
Open science0.0020.011
Research integrity0.0100.011
Insufficient payload (model declined to judge)0.0100.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.394
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations89
Published2018
Admission routes1
Has abstractyes

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