A157 INCIDENCE OF VENOUS THROMBOEMBOLIC EVENTS IN PATIENTS WITH ULCERTIVE COLITIS DURING HOSPITALIZED AND POST-DISCHARGE SETTINGS
Bibliographic record
Abstract
Patients with inflammatory bowel disease (IBD) are at increased risk of venous thromboembolism (VTE) events. Hospitalized patients carry a higher risk for VTE events and as such guidelines recommend thromboprophylaxis for all admitted IBD patients. Risk of VTE in the post-discharge setting has not been as well defined; therefore, it remains unknown if extended thromboprophylaxis is warranted. To compare the incidence of VTE events in patients with ulcerative colitis (UC) during hospitalized and post-discharge settings. A retrospective observational study was conducted on consecutive UC patients admitted to The Ottawa Hospital with a disease flare between April 1 2006 and April 30 2012. Symptomatic VTE events were assessed during hospitalization and up to 1-year post-discharge through chart review. Of the 184 patients included, average length of stay was 12.3 days. Ninety four (51%) patients were male, with a median age of 41 years and 23% were current or ex-smokers. Thirty eight percent of all patients received prophylactic or full dose anticoagulation during admission. Overall 17 patients (9%) developed a VTE; 13 (7%) of inpatients and 4 (2%) of outpatients. The median time to diagnosis of outpatient VTE was 4 days (range 4–9 days). Of all VTE patients, 35% received thromboprophylaxis; 45% of inpatients and 25% of outpatients. Of all VTE patients, 82% received corticosteroids, 15% received biologics and 12% underwent colectomy during hospitalization. Of the patients who developed outpatient VTE, all were treated with corticosteroids and 1 (25%) with biologics. None of these patients underwent colectomy. Table 1 describes the individual outpatient VTE events. In this small retrospective study VTE events were rare in patients with UC following discharge from hospital. Future studies with larger sample sizes are required to confirm these findings and to identify predictors of high-risk patients who may benefit from extended thromboprophylaxis. Table 1. *Yes: therapeutic fragmin given history of VTE None
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".