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Record W2797934830 · doi:10.1002/ejhf.1000

April 2018 at a Glance: Focus on Prognostic Variables

2018· article· en· W2797934830 on OpenAlexaff
Marco Metra

Bibliographic record

VenueEuropean Journal of Heart Failure · 2018
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Function and Risk Factors
Canadian institutionsSurgical Specialties (Canada)
Fundersnot available
KeywordsMedicineInternal medicineHeart failureEjection fractionCardiologyAliskirenNatriuretic peptideBrain natriuretic peptideMyocardial infarctionDiabetes mellitusBiomarkerRenin–angiotensin systemBlood pressureEndocrinology

Abstract

fetched live from OpenAlex

Prediction of heart failureBhambhani et al. 1 pooled data from four community-based longitudinal cohorts, including 28 820 subjects free of heart failure (HF) at entry and followed for 12 years, to identify predictive variables for the development of HF with mid-range ejection fraction (HFmrEF), compared with HF with reduced (HFrEF) or preserved ejection fraction (HFpEF).Clinical predictors of HFmrEF included age, male sex, systolic blood pressure, diabetes mellitus, prior myocardial infarction, natriuretic peptides, cystatin-C, and high-sensitivity troponin.Natriuretic peptides were also the strongest predictors of HFrEF.All-cause mortality following the onset of HFmrEF was similar to that of HFrEF and worse than that of HFpEF. 1 Similarities between HFmrEF and HFrEF are therefore confirmed with respect to their risk factors, whereas the outcome of HFmrEF patients has been often found as better compared to that of HFrEF patients.2 Delles et al. 3 studied by nuclear magnetic resonance-based metabolomics two cohorts of subjects at risk of cardiovascular events and identified, among 80 metabolites, phenylalanine as a predictor of incident HF hospitalizations.Although its additive predictive value was modest, it remained significant after adjustment for baseline variables and natriuretic peptide plasma levels. Cardiac amyloidosisSiegismund et al. 15 analysed endomyocardial biopsies from 54 consecutive patients with amyloidosis.Patients with cardiac amyloid light-chain (AL) amyloidosis had a poorer prognosis than those

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.027
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.065
Threshold uncertainty score0.216

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.027
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0060.005
Open science0.0020.003
Research integrity0.0030.007
Insufficient payload (model declined to judge)0.0650.029

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.234
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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