0132 Oscillating Inspiratory Flow Limitation in Cheyne-Stokes Breathing
Bibliographic record
Abstract
Cheyne-Stokes breathing (CSB) is thought to be of central rather than obstructive origin. Our aim was to confirm anecdotally observed inspiratory flow limitation (IFL), a marker of obstruction, in CSB. Of 66 774 sleep polygraphs submitted for diagnostic interpretation (www.sagatech.ca) 30 (0.045%) were reported to have CSB and have acceptable signal quality. Patented breath-by-breath automated IFL scoring of the flow signal was performed. Manual and automated CSB scoring were also applied. All 30 polygraphs scored positive for CSB using automated analysis, but only 10 on manual review had oscillating crescendo-decrescendo flow amplitude, alternating apnoea on flow signal, absent snoring, and sinusoidal oximetry. All 10 true positive studies, but none of the 20 false positive tests, had oscillating crescendo-decrescendo IFL. Oscillating IFL is ubiquitous in true CSB suggesting mixed central and obstructive origins. CSB detection could be improved by applying both standard definitions and IFL analysis. None.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".