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Record W2800282036 · doi:10.5206/uwomj.v87i1.1895

The role of medical cannabis in the opioid crisis

2018· article· en· W2800282036 on OpenAlexvenueno aff
Lucy Samoilov, Claire P Browne

Bibliographic record

VenueUniversity of Western Ontario Medical Journal · 2018
Typearticle
Languageen
FieldMedicine
TopicCannabis and Cannabinoid Research
Canadian institutionsnot available
Fundersnot available
KeywordsCannabisOpioidMedicineAddictionCannabinoidPsychiatryChronic painLegalizationAdverse effectPharmacologyInternal medicine

Abstract

fetched live from OpenAlex

Opioid use increased dramatically in the 1990s upon introduction of newer, more relaxed regulations. As opioid prescriptions for pain increased, a parallel increase in opioid abuse and addiction occurred; this phenomenon is widely known as the opioid crisis. Cannabis had long been considered a recreational drug until legislation in 2001 allowed highly limited access to the drug for medicinal purposes. Although small-scale clinical trials show promising results for the use of cannabis in pain management, it is not currently indicated for chronic or severe-to-moderate acute pain, for which opioids are typically considered the standard of care. The impending legalization of recreational cannabis may mark a turning point in pain medicine as the general public becomes able to selfmedicate with cannabis. This increased availability may lead individuals prescribed opioids to combine or replace them with cannabis, with potential positive impacts. There is growing evidence that cannabinoid compounds present in cannabis are able to augment opioid-induced pain relief. Increased availability of cannabis is linked to decreased opioid-related mortality and hospitalizations; furthermore, cannabis might act as a tool to treat opioid addiction. Cannabis does possess adverse effects and addiction risk, and expanded research into its properties is needed. However, its relatively decreased risk profile and potential positive effects indicate that it may serve an important role in addressing the opioid crisis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.482
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.264
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2018
Admission routes1
Has abstractyes

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