SP638ABNORMALITIES OF COGNITIVE FUNCTION IN PATIENTS UNDERGOING HEMODIALYSIS AND ITS ASSOCIATION WITH SLEEP QUALITY
Bibliographic record
Abstract
INTRODUCTION AND AIMS: Cognitive impairment (CI) is common in patients with chronic kidney disease. In dialysis patients, cognitive impairment is associated with increased resource utilization, higher risk of hospitalization and all-cause morbidity. In patients with chronic disease, sleep disorders are more prevalent, poor sleep quality can negatively affect immunity, cognitive functions, and emotional manifestations. The aim of this study is identify the abnormalities of cognitive function and find its association with sleep quality in end stage renal disease (ESRD) patients undergoing routine hemodialysis METHODS: This is a cross sectional study that took place in four hemodialysis clinics in Jakarta, Indonesia. Patients which had undergone hemodialysis for more than 3 months were included in this study. Cognitive function was assessed using Montreal Cognitive Assessment (MoCA-Ina). Cognitive impairment was defined as MoCA score less than 26. Sleep quality was assessed using Pittsburg Sleep Quality Index (PSQI). Analysis was done using Mann-Whitney U Test. RESULTS: A total of 113 patients were included in this study, out of which 72 (63.7%) were male. The mean age of the patients was 53.2 (±12.5) years. The most common etiology of chronic kidney disease was due to hypertension (58.4%), followed by diabetes mellitus (29.2%). Cognitive impairment was present in 97 (85.8%) patients. The median scores of visuospatial, naming, attention, language, abstraction, delayed recall and orientation domains were 3 (0-5), 3 (0-3), 4 (0-6), 2 (0-3), 1 (0-2), 0 (0-5) and 6 (0-6) respectively. Cognitive impairment had significant association with sleep quality (P = 0.026). The median sleep quality score in patients with and without cognitive impairment were 12 (0 - 21) and 8.5 (2 - 16) respectively. CONCLUSIONS: More than half of the patients in our study have cognitive impairment. Cognitive impairment has significant association with sleep quality in hemodialysis patients. As physicians, we should try to modify the sleep quality in order to improve the cognitive function of these patients.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".