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Cognitive Function in Varsity Football Athletes is Maintained in the Absence of Concussion

2017· article· en· W2805320445 on OpenAlexafffundabout
Danielle Brewer‐Deluce, Timothy D. Wilson, Adrian M. Owen

Bibliographic record

VenueThe FASEB Journal · 2017
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsWestern University
FundersCanada Excellence Research Chairs, Government of Canada
KeywordsConcussionChronic traumatic encephalopathyAthletesCognitionAmerican footballPopulationPsychologyFootballPhysical therapyCognitive testMedicinePhysical medicine and rehabilitationGerontologyClinical psychologyPoison controlInjury preventionPsychiatry

Abstract

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Introduction Repetitive sub‐clinical head impacts (SHI) are linked to progressive cognitive decline and post mortem chronic traumatic encephalopathy (CTE) diagnoses in pro contact‐sport athletes. This is particularly evident in aging, though there remains a paucity of knowledge surrounding the onset of trauma‐related cognitive decline in younger athletes. In addition, the influence of cumulative SHI, particularly in the absence of concussion, is poorly understood. As such, we tested the hypothesis that cognitive function would be impaired as a function of career‐long and season‐long exposure to SHI in varsity (collegiate‐level) American football athletes. Methods Male varsity football athletes (n = 31, age 22.3 ± 1.6) completed the Cambridge Brain Sciences (CBS) cognitive battery before (pre) and after (post) their football season. Scores were compared in a repeated measures design against an age (20.6 ± 1.2) and sex matched control group (n = 35) who completed cognitive testing at the same time interval. Individuals sustaining a concussion within the past year were excluded. The CBS cognitive battery ( www.cambridgebrainsciences.com ) consists of 12 online tests assessing a broad range of cognitive skills. Previous work by Hampshire et al (2012) used PCA to identify 3 functionally and cortically distinct networks tested by the CBS battery: Short Term Memory, Reasoning, and Verbal Ability. Based on their previously established factor loadings, a linear composite score for each of these 3 networks was calculated for preseason raw scores. Previously established age‐ and sex‐matched normative values for this population (n > 18 000) were also compared to preseason scores. Postseason control tests are ongoing and were excluded from network and normative comparisons as the current literature does not address the effects of repeated testing on scores. Results In the preseason, there were no significant differences between footballers and controls on any of the 12 CBS tests. Preliminary results suggest that across the season, footballer and control participant scores do not differ either between groups or within groups compared to preseason scores (see ). MANOVA – F(36,276) = 1.336, p = 0.148, η 2 = 0.387. In terms of the network linear composite scores, there were no significant differences between controls and football athletes (see ) for any network. MANOVA – F(3, 61) = 0.55, p = 0.65, η 2 = 0.026. Lastly, in comparison to normative values, football athletes differed on 6 tests of cognitive function, and controls differed from the normative scores on 4 tests (indicated with “N” in ) at the preseason time point. Conclusions Overall, these results suggest the maintenance of normal cognitive function, as assessed behaviourally, in the absence of concussion in an elite contact‐sport population. Small differences between normative and sample means warrant further exploration focussed on examining the functional implications of cumulative SHI as behavioural decline may be masked by compensatory neural mechanisms. Support or Funding Information Canada Excellence Research Chair funding to A.M. Owen

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.029

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.353
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations3
Published2017
Admission routes3
Has abstractyes

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