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Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial

2018· article· en· 2,536 citations· W2805592007 on OpenAlex· 10.1016/s1470-2045(18)30351-6

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
The Lancet Oncology
Topic
Hepatocellular Carcinoma Treatment and Prognosis
Field
Medicine
Canadian institutions
University of TorontoPrincess Margaret Cancer Centre
Funders
Merck
Keywords
MedicinePembrolizumabSorafenibInternal medicineClinical endpointHepatocellular carcinomaAdverse effectResponse Evaluation Criteria in Solid TumorsPopulationOncologyDiscontinuationClinical trialPhases of clinical researchSurgeryCancerImmunotherapy
Has abstract in OpenAlex
no