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Record W2807531956 · doi:10.14740/jocmr3422w

Characteristics and Factors Associated With the Mortality of Hypotensive Patients Attending the Emergency Department

2018· article· en· W2807531956 on OpenAlexvenueno aff
Kumpol Amnuaypattanapon, Suwimon Khansompop

Bibliographic record

VenueJournal of Clinical Medicine Research · 2018
Typearticle
Languageen
FieldMedicine
TopicHemodynamic Monitoring and Therapy
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineInterquartile rangeCase fatality rateBlood pressureOdds ratioMortality rateConfidence intervalEmergency departmentMean arterial pressureSeptic shockResuscitationShock (circulatory)SepsisEpidemiologyAnesthesiaInternal medicineHeart rate

Abstract

fetched live from OpenAlex

BACKGROUND: The prevalence of hypotension in emergency departments (EDs) is approximately 1-2%, but is associated with a mortality rate of 8-15%. There has never been a study in Thailand examining the epidemiology or the risk factors for early mortality of patients presenting with hypotension in the ED. Therefore, this study aimed to define the characteristics, mortality rate within 48 h and associated factors of hypotensive patients at ED. METHODS: Data of patients with hypotension attending the ED of Thammasat University Hospital (TUH) were retrospectively studied. RESULTS: Of the 9,000 patients seen in the TUH ED, 233 were hypotensive for a prevalence of 2.5%. Patients were old, with a mean age of 61 ± 20 years. The most common presenting symptom was fever, and sepsis was the most common cause of hypotension. The mean systolic blood pressure (SBP) was 78 ± 8 mm Hg. Isotonic crystalloid volume resuscitation in first hour was 758 mL (interquartile range (IQR), 500 - 1,000) and the total volume to achieve a mean arterial pressure (MAP) ≥ 65 mm Hg was 1,142 mL (IQR, 500 - 1,500). Twenty-seven percent of patients needed vasopressor support. Nineteen patients died ≤ 48 h, giving a case fatality rate of 8.2%. Three independent factors associated with 48-h mortality were initial pulse rate > 100 beats/min (odds ratio (OR), 4.21; 95% confidence interval (CI), 1.05 - 16.88; P = 0.042), diagnosis of shock (OR, 13.74 (1.49 - 126.61); P = 0.021) and recurrent hypotension (OR, 6.91 (1.54 - 30.99); P = 0.012). CONCLUSIONS: Hypotension in the ED was common and associated with high mortality rate. Better triage, patient monitoring and treatment may improve outcomes in these patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.010
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0080.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.288
GPT teacher head0.524
Teacher spread0.236 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2018
Admission routes1
Has abstractyes

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