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Record W2808969327 · doi:10.1016/s0167-8140(18)31473-7

EP-1163: Partial Laryngectomy vs Definitive Radiotherapy: 10 year-Outcomes in T2N0 Glottic Cancer

2018· article· en· W2808969327 on OpenAlexaff
L. Dos Santos Fonseca, Alberto Mota, E. Netto, S. Esteves, R. Pocinho, M. Labareda, F. Santos, Miguel Magalhães

Bibliographic record

VenueRadiotherapy and Oncology · 2018
Typearticle
Languageen
FieldMedicine
TopicHead and Neck Cancer Studies
Canadian institutionsBC Cancer AgencyOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsLaryngectomyMedicineRadiation therapySurgeryLarynx

Abstract

fetched live from OpenAlex

Purpose or ObjectiveRadiotherapy alone has been standard management for early stage glottis cancer for decades.Various fractionation regimens exist, but hypofractionation has been proven to lead to better outcomes.Second malignancy is a concern in these patients who have long life expectancies.We reviewed our experience to determine if radiotherapy was associated with an increase in the risk of second malignancies. Material and MethodsWe retrospectively reviewed consecutive patients treated with radiotherapy for T1-T2 glottis cancer b etween January 2006 and January 2013.From 2006, all patients with early glottis cancer received hypofractionated treatments at our regional tertiary center.89%, received 52,0 Gy in 20 fractions over 4 weeks.82% were treated with 6 MV photons and 18% with Cobalt using either wedged laterals or 3DCRT with 2-4 fields.Patients were treated supine with appropriate bolus, and immobilized with a thermoplastic shell.Patient information was stored in our head and neck registry database.Baseline

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.003
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.363
Teacher spread0.333 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractno

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