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Record W2809846589 · doi:10.1016/j.jaci.2018.06.022

Genetic variants with gene regulatory effects are associated with diisocyanate-induced asthma

2018· article· en· W2809846589 on OpenAlexaff
David I. Bernstein, Zana L. Lummus, Banu Kesavalu, Jianbo Yao, Leah C. Kottyan, Daniel Miller, André Cartier, María Jesús Cruz, Catherine Lemière, Xavier Muñoz, Santiago Quirce, Susan M. Tarlo, J. Sastre, Louis Philippe Boulet, Matthew T. Weirauch, Kenneth M. Kaufman

Bibliographic record

VenueJournal of Allergy and Clinical Immunology · 2018
Typearticle
Languageen
FieldMedicine
TopicOccupational exposure and asthma
Canadian institutionsUniversité LavalInstitut Universitaire de Cardiologie et de Pneumologie de QuébecUniversity of TorontoUniversité de MontréalHôpital du Sacré-Cœur de Montréal
FundersNational Institute for Occupational Safety and HealthNational Center for Research ResourcesNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNational Human Genome Research Institute
KeywordsSingle-nucleotide polymorphismBiologyGeneGeneticsElectrophoretic mobility shift assayMolecular biologyAllelePromoterGene expressionGenotype

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.257
Threshold uncertainty score0.401

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.290
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2018
Admission routes1
Has abstractno

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